A Detailed Literature Review on Primary Lymphoma of Bone
Primary Bone Lymphoma (PLB) is a very unusual neoplasm, most often associated with bone pain and swelling, or as an unintentional imaging finding. The median diagnostic age is 55 years (range 50-60) with the predominance of males. In the paediatric and young adult population, PLB is highly rare. Diagnosis of PLB includes tissue biopsy and the most common subtype is Non-lymphoma Hodgkin’s (NHL). Thoracic-abdominal-pelvic computed tomography (CT) scan, bone marrow biopsy and cytology of cerebrospinal fluid are used for disease staging. PLB is a rare lymphoma subtype with a favourable prognosis, characterised in most cases by localised disease Consolidation of chemo-immunotherapy with radiotherapy (RT) is a commonly used treatment technique with good results obtained for PLB.
Dr. E. Elhassadi
University Hospital Waterford, Waterford, Ireland.
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