A Novel Optical Oximeter via Absorption Spectra-Based CO2 Laser Photothermal Effects

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A Novel Optical Oximeter via Absorption Spectra-Based CO2 Laser Photothermal Effects

September 2, 2020 BIOLOGY 0

Spectroscopic and histological study of CO2 laser interaction with rats tissues were carried out. We

detected for the first time the changes in optical absorption spectra of rat’s tissues with selective CO2

laser optical densities ranging from 20.64 to 34.40W/cm2. The laser exposed tissues show higher

absorbance in hemoglobin than that for the unexposed tissue. Using the same laser and same optical

densities, the absorption spectra of fresh blood were measured. Much intense peaks of hemoglobin in

the exposed fresh blood than that for the corresponding peaks for the tissue were detected. A scheme

based on recent experimental findings is proposed for explanation of this novel phenomenon. The

histological study shows thermal damage of blood vessels localized at the dermis layer. At high laser

optical densities a vessel rupture with hemorrhage were occurred. The results indicate a pronounced

modification of skin absorption properties by laser irradiation. Such an effect is due to thermally

induced biophysical and biochemical processes inside the highly heterogeneous tissue structure. A

clinical oximeter can be optimized by using CO2 laser Photothermal effects This device plays an

important role during COVID-19 pandemic.

 

Author (s) Details

Hassan H. Mohammed

Physics Department, College of Science, University of Basrah, Basrah, Iraq and Iraq University College, Department of Computer Engineering Technology, Alestiqlal Street, Basrah, Iraq.

Muzahim M. Abdullah

Physics Department, College of Science, University of Basrah, Basrah, Iraq.

Amjad Al-Asadi

Physics Department, College of Science, University of Basrah, Basrah, Iraq.

View Book :- https://bp.bookpi.org/index.php/bpi/catalog/book/239

 

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