A Scientific Study: Analysis of Brain-Neuromuscular Synchronization and Coupling Strength in Muscular Dystrophy after NPT Treatment

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A Scientific Study: Analysis of Brain-Neuromuscular Synchronization and Coupling Strength in Muscular Dystrophy after NPT Treatment

July 31, 2020 MEDICAL 0

We perform an analysis of brain-neuromuscular synchronization and coupling strength in muscular
dystrophy before and after NPT treatment. In order to estimate with accuracy the level of brain
synchronization, we introduce and use the method of the cross GMI that was elaborated by Pompe.
The finality is to account for the nonlinear chaotic dynamic contributions that regulate the dynamics.
We find that this method is excellent and it may be applied in such case of sEMG and EEG study as
well as at a general neurological level. By it we arrive to quantify the coupling strength and
synchronization first between two muscular sections (left and right trapezes) and after between Brain
activity, as recorded by the EEG, and the trapezes. We compare the results before and after the NPT
treatment and we find that the improvement obtained following such treatment is very consistent. We
have now in progress other studies relating in particular the application of such new methodologies to
other more serious pathologies as the HSP (Hereditary Spastic Paraplegia).

Author (s) Details

Elio Conte
School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy and Department of Basic Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

Ken Ware
The International NeuroPhysics Functional Performance Institute, Robina, Australia.

Riccardo Marvulli
School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy and Department of Physical Medicine and Rehabilitation, University of Bari Aldo Moro, Bari, Italy.

Giancarlo Ianieri
School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy and Department of Physical Medicine and Rehabilitation, University of Bari Aldo Moro, Bari, Italy.

Marisa Megna
School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy and Department of Physical Medicine and Rehabilitation, University of Bari Aldo Moro, Bari, Italy.

Sergio Conte
School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy.

Leonardo Mendolicchio
School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy.

Enrico Pierangeli
School of Advanced International Studies on Applied Theoretical and Non Linear Methodologies of Physics, Bari, Italy.

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