A Study of the Correlation between Brain-type Natriuretic Peptide (BNP) Levels & Left Ventricular Ejection Fraction (LVEF) in Heart Failure

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A Study of the Correlation between Brain-type Natriuretic Peptide (BNP) Levels & Left Ventricular Ejection Fraction (LVEF) in Heart Failure

September 10, 2021 Medicine and Medical Research 0

Background: A large number of patients with heart failure have a maintained ejection fraction. It’s difficult to tell the difference between heart failure with a reduced ejection fraction and heart failure with a preserved ejection fraction. The study’s goals are as follows:

BNP levels were measured in patients with heart failure who had a preserved LV ejection fraction as well as those who had a reduced LV ejection fraction.

To see if BNP can be used to diagnose heart failure with preserved LV ejection fraction in both groups and to see if BNP can be used to diagnose heart failure with preserved LV ejection fraction].

Methods: The medical records of young patients (20–40 years old) diagnosed with Heart Failure and admitted between 2014 and 2015 were examined in order to determine the proportion of patients with preserved vs reduced ejection fraction, as well as the relationship between their Brain-type Natriuretic Peptide (BNP) levels and Left Ventricular Ejection Fraction (LVEF) in both the grou

Following statistical analysis, it was discovered that approximately 36% of heart failure patients had preserved ejection fraction. In both heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF), there was a negative connection between BNP levels and LVEF (HFpEF). Females made up the majority of the patients in the HFpEF group. The HFpEF group’s mean BNP level was substantially lower than the HFrEF group’s.

Conclusion: Heart Failure with maintained systolic function affects about one-third of patients, the majority of whom are women. In both groups, there is a considerable negative connection between BNP levels and LVEF percent. BNP levels can thus be utilised to distinguish between HFpEF and HFrEF.

Author (S) Details

V. Veena
Department of Biochemistry, Saveetha Medical College, Thandalam, Tamil Nadu, India.

Ganesh
Department of Biochemistry, Sri Ramachandra Medical College & Research Institute, Chennai, Tamil Nadu, India.

Santhi Silambanan
Department of Biochemistry, Sri Ramachandra Medical College & Research Institute, Chennai, Tamil Nadu, India.

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