An In-vitro and In-vivo Study of Antioxidant Potential of Green Synthesized Flavonoid Loaded Mono and Bimetallic Nanoparticles

Science Press Release Distribution Services

An In-vitro and In-vivo Study of Antioxidant Potential of Green Synthesized Flavonoid Loaded Mono and Bimetallic Nanoparticles

March 13, 2021 Chemistry and Biochemistry 0

Nanotechnology’s remarkable performance has unwrapped the vision for creating mono and multimetallic nanoparticles with a wide variety of applications due to their distinct conduct. Gold and silver nanoparticles have made considerable strides in biomedical science, in particular. The study uses flavonoids extracted from the bark of the Madhuca longifolia plant to fabricate mono (Au, Ag) and bimetallic (Au-Ag) nanoparticles in a single phase that is environmentally friendly. The effect of architecture on the action of monometallic (Au, Ag) and bimetallic (Au-Ag) nanoparticles in terms of antioxidant bio-efficacy has been investigated. Compared to monometallic nanoparticles, bimetallic (Au-Ag) nanoparticles have a higher antioxidant bio-efficacy. A preliminary mechanism for bimetallic nanoparticles’ higher antioxidant bio-efficacy has been proposed based on our experiments and relevant details. HPTLC fingerprinting was used to demonstrate the capping of medicinally essential flavonoids on freshly generated metal nanoparticles for improved target bio-efficacy. The proposed green nanotechnological strategy for the fabrication of bimetallic nanoparticles appears to be an excellent approach for improving antioxidant bio-efficacy without undergoing synthetic structural changes.

Author(s) Details

Miss. Mukti Sharma
Department of Chemistry, Faculty of Science, Dayalbagh Educational Institute, Agra 282005, India.

Saurabh Yadav
Department of Chemistry, Faculty of Science, Dayalbagh Educational Institute, Agra 282005, India.

Dr. Narayanan Ganesh
Jawaharlal Nehru Cancer Hospital & Research Centre Bhopal, 462001, India.

Professor, Dr. Man Mohan Srivastava
Department of Chemistry, Faculty of Science, Dayalbagh Educational Institute, Agra 282005, India.

Professor, Dr. Shalini Srivastava
Department of Chemistry, Faculty of Science, Dayalbagh Educational Institute, Agra 282005, India.

View Book :- https://stm.bookpi.org/CACB-V3/issue/view/57

 

Leave a Reply

Your email address will not be published. Required fields are marked *