Category: MEDICAL

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Flupirtine: An Exigency Call for Medication Vigilant

The purpose of this monograph is to provide an extensive review of the drug Flupirtine clinical applications and its safety-related issues. While existing Non- Steroidal Anti-inflammatory Drugs (NSAIDs) and Opioids which are used in the treatment of pain had some common adverse effects this drug is devoid of adverse effects exhibited by NSAIDs and Opioids…
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August 28, 2020 0

How a Crowded Emergency Department Became Non-crowded and Crowded Back within 10 Years: Is It an ED Leadership Failure or a Hospital Leadership Failure, or Maybe Both?

Background: from 1993 until 2013 our Emergency Department (ED) went through three periods, with different ED manager each. Although the number of beds, visits and admissions during these three periods didn’t change significantly, a change in the ED’s policy, without a change in the hospital’s policy, converted a very crowded ED to a non-crowded one…
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August 26, 2020 0

Epidemiology of Fracture Dislocations

Introduction: Fractures and dislocations are a significant public health and economic burden but the epidemiology of fracture dislocations is poorly understood. This study aimed to evaluate the prevalence and distribution of various fracture dislocations. Materials and Methods: Fracture dislocation cases who underwent closed reduction by a general surgeon where no Orthopaedician was available were recorded.…
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August 26, 2020 0

Application of Radiographic Stent for Simplified Placement of Implants in the Mandible

This article aims to present a modified yet simple technique for the placement of implants between the mandibular foramina with the help of a radiographic stent. A radiographic stent was made on the patient’s mandibular cast on which two metal balls were fixed at the premolar area and this was then used to determine the…
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August 26, 2020 0

Experiment with Personalised Dosing of Hyperthermia

Objective: Our objective is to show the superiority of the membrane selection and connected energy dose fixed via personal sensing. Method: Hyperthermia in oncology involves heating malignant cells and causing thermal damage in an attempt to destroy them. This could be immediate (necrotic) cell-distortion and ignite natural cell elimination, like apoptosis or autophagy. Two concepts…
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August 26, 2020 0

Anti-Helicobacter pylori, Antisecretory and Healing Effects of Aqueous Extract of Eremomastax speciosa (Acanthaceae) on Unhealed Gastric Ulcers

Objective: This work investigated the In vitro and In vivo anti Helicobacter pylori activity, and the healing and antisecretory effects of the aqueous extract of Eremomastax speciosa on “unhealed gastric ulcers” associated with gastric acid hypersecretion. Materials and Methods: H. pylori isolates were obtained from gastric biopsies collected in the Civil hospital, Karachi. In vitro…
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August 26, 2020 0

Lichenoid Drug Eruptions: An Overview

Lichenoid skin disorders are a group of dermatological manifestations associated with flat topped itchy and scaly skin. These are also well known as drug induced lichen planus and are result of cutaneous adverse effects by most drugs. Offending agents involved in the lichenoid disorders are Antimalarial, Antidiuretics, Antihypertensive and Non-Steroidal Anti- inflammatory drugs (NSAIDs) etc.…
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August 26, 2020 0

Critical Overview: Ocular Angiogenesis

Angiogenesis is the formation of new blood vessels from preexisting vasculature, being mediated and regulated by a complex composed of growth factors, cytokines, cell signaling molecules and extracellular matrix components. The most important pro-angiogenesis regulator molecules are vascular endothelial factor (VEGF), fibroblasts growth factors (FGFs), hypoxia-inducible factor 1 (HIF- 1), platelet-derived growth factor (PDGF) and…
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August 26, 2020 0

Usefulness of Echocardiography in the Management of Heart Failure

Morbidity and mortality from heart failure is on the increase globally due to rising prevalence rates and lack of appropriate evaluation and therapy. Approximately 50% of heart failure patients present with evidence of left ventricular systolic dysfunction. This is manifested as low left ventricular ejection fraction and is also called Heart failure with reduced ejection…
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August 26, 2020 0

A Progressive Case Report of Choledochocele Unclassifiable by Sarris’s Classification Characterized by the Serial Images of Endoscopic Retrograde Cholangiopancreatography [ERCP]

A 74-year-old Japanese housewife was shown to have a large, smooth-surfaced, protruding, semipedunculated tumor covered with the normal-appearing mucosa on the posteromedial wall of the mid descending part of the duodenum immediately oral to the papilla of Vater by endoscopy. ERCP demonstrated the normal main and accessory pancreatic ducts. Just after abruptly contracted, the terminal…
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August 26, 2020 0