Category: Pharmaceutical

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A Renewable Relationship between Epilepsy and Quinazolinones

 There must be a global response to the public health problem of epilepsy. No matter where it occurs in the world, epilepsy affects people of all ages, genders, races, and social backgrounds. The cortical area of the brain’s excessive cortical neuron firing frequently results in the epileptic condition. Understanding the different types of epileptic episodes…
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August 6, 2022 0

Topical Gel Loaded with Fluconazole Niosomes: Formulation and Evaluation Study

 Designing and evaluating topical gel-loaded fluconazole niosomes is the aim of the project. Fluconazole, a macrolide antibiotic, is used to treat a number of delicate bacteria. Niosomes can boost a drug’s skin penetration and lengthen its duration in the stratum corneum and epidermis while decreasing its absorption throughout the body. Because they may change pharmacokinetics…
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August 6, 2022 0

Management of Post-Operative Pain and Quality of Life of Total Knee Arthroplasty Patients: A Prospective Study

The purpose of this study is to assess the effects of pregabalin on post-operative pain management and patients with osteoarthritis’ (OA) quality of life (QOL) after total knee arthroplasty. The orthopaedics department conducted this prospective observational research. There were two groups each with 96 patients. 50 patients in Group A are treated with nonsteroidal anti-inflammatory…
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August 6, 2022 0

Effect of Ethanolic Extract of Solanum torvum Leaf on Liver of Treated Rats: A recent study approach

 In conventional medicine, the plant solanum torvum is frequently employed. This study’s objective was to assess how treated Wistar rats’ livers responded to an ethanol extract of Solanum torvum leaf. S. torvum leaves that had just been collected were shade-dried and milled into a fine powder. ethanol was macerated with 500 g of powdered plant…
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August 6, 2022 0

A Systematic Review on Metabolite Profiling in Anticancer Drug Development

 Drug metabolism is one of the most significant pharmacokinetic processes and is essential to the creation of new medications. Because the metabolites generated may be beneficial for therapy or seriously harmful, it is crucial to examine the metabolite profile. The purpose of this systematic review is to provide an overview of the literature on the…
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August 5, 2022 0

Effect of Hydroxy Propyl Cellulose and Eudragit Polymers on Delayed Release Pellet Systems

 The goal of the current study is to create and assess omeprazole magnesium delayed release pellets for the treatment of acid reflux and ulcers utilising the drug stacking approach with a fluid bed processor. Omeprazole magnesium saturated solutions in a variety of non-volatile solvents, including methanol, ethanol, acetone, isopropanol, and water, were prepared for solubility…
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August 5, 2022 0

Effect of Moringa oleifera on Atherogenic Lipoprotein Indices of HIV Infected Adults on Tenofovir-Based Antiretroviral Regimen in UPTH, Nigeria

The use of the antiviral regimen Tenofovir (TDF) based (Tenofovir/Lamivudine/Efavirenz) for the treatment of HIV has been linked to dyslipidaemia, which is linked to cardiovascular problems and a shorter life span. The study assessed the impact of Moringa oleifera supplementation on metabolic anomalies related to HIV patients on TDF-based regimen using a randomised comparative experiment.…
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August 5, 2022 0

Pharmacotherapeutic Potential of Lawsonia inermis L.: Implications and Future Prospective

Both therapeutic and economic uses have been discovered for henna (Lawsonia inermis). Mehendi is made from the pigment lawsone, which is obtained from this plant. The henna plant contains a large number of secondary metabolites, which provide it medicinal qualities such as anticarcinogenic, antidiabetic, analgesic, immunostimulatory, and many others. This produces a big demand pressure…
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February 18, 2022 0

Evaluation of Hepatoprotective Activity of Vitex negundo Linn. against Paracetamol Induced Hepatotoxicity in Rats

The purpose of this study was to determine the hepatoprotective efficacy of an ethanolic extract of Vitex negundo Linn leaves. Vitex negundo Linn. is a medicinal plant that can be found all across India. It is a short Mediterranean plant that is utilised as a folkloric herbal treatment. Methods: The ethanolic extract of Vitex. Negundo…
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February 18, 2022 0

A Stability Indicating RP-HPLC Method Validation for Simultaneous Estimation of Linagliptin and Empagliflozin in Pharmaceutical Dosage Form

Aims: Linagliptin and Empagliflozin are a new medicine combination for the treatment of Diabetes Mellitus, one of humanity’s oldest and most fatal diseases. The goal of this study was to develop and validate a new, quick, sensitive, specific, and stable stability indicating analytical approach for the simultaneous estimation of Linagliptin and Empagliflozin in a fixed…
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February 18, 2022 0