Comparison between Neurocysticercosis (NCC) and Central Nervous System (CNS) Tuberculoma in Children: Dilemma over Clinico-Radiological Diagnosis?

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Comparison between Neurocysticercosis (NCC) and Central Nervous System (CNS) Tuberculoma in Children: Dilemma over Clinico-Radiological Diagnosis?

July 16, 2021 Medicine and Medical Science 0

Background: The clinical presentations and imaging of neurocysticercosis (NCC) and central nervous system (CNS) tuberculomas frequently coincide. Despite the fact that the aetio-pathology in both scenarios is completely different, there is a lot of confusion in their clinico-radiological evaluation because the findings and appearances are very similar in many respects. In the background of their presentation, the emphasis should be placed on the salient features of each entity. The goal of the investigation was to show how the clinico-radiological findings in both entities differed.

Materials and Methods: Ten patients aged 5 to 15 years (mean age 10.4 years) with headaches and/or seizures had MRI alone or in combination with CT scans. In all of the instances, basic T1W, T2W, T2W FLAIR, and T1W contrast tests were performed. Only three patients had CT scans, and two of them received contrast.

Results: In post-contrast MRI, eight patients showed ring enhancing lesions, whereas two had just cystic lesions ranging from 1 to 3 cm in diameter.

Conclusion: Both modalities verified seven cases of tuberculomas, with one case remaining inconclusive. According to the findings, two instances were diagnosed with neurocysticercosis. The goal of distinguishing between NCC and tuberculomas in the brain was a fair achievable goal, and it was met. In several situations, contrast MRI and spectroscopy revealed a variety of findings for the different features. The results of MR spectroscopy show a lipid peak in the first and an amino acid peak in the second.

Author (S) Details

Bharat Bhushan Sharma
Department of Radiodiagnosis, SGT Medical College & RI, SGT University, Gurugram, Haryana, 122505, India.

Shashi Sharma
Department of Paediatrics, SGT Medical college & RI, SGT University, Gurugram, Haryana, 122505, India.

Natasha Nargotra
Department of Radiodiagnosis, SGT Medical College & RI, SGT University, Gurugram, Haryana, 122505, India.

Nalin Chugh
Department of Radiodiagnosis, SGT Medical College & RI, SGT University, Gurugram, Haryana, 122505, India.

Ritu Dhaka
Department of Radiodiagnosis, SGT Medical College & RI, SGT University, Gurugram, Haryana, 122505, India.

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