Extended Spectrum β-Lactamase in Escherichia coli and Klebsiella pneumoniae: Trends in Hematopoietic Stem Cell Transplant Recipients

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Extended Spectrum β-Lactamase in Escherichia coli and Klebsiella pneumoniae: Trends in Hematopoietic Stem Cell Transplant Recipients

June 7, 2021 Disease and Health 0

During a 10-year period, we conducted an extended spectrum-lactamase (ESBL) survey among infectious Escherichia coli and Klebsiella pneumoniae clinical isolates at Tunisia’s Bone Marrow Transplant Centre (from 2002 to 2011).

Bacterial identification was accomplished out using biochemical features as well as API identification techniques. The disc diffusion method was used to investigate antibiotic susceptibility on Muller-Hinton agar.

ESBL-producing strains were found in 34.5 percent of 142 K. pneumoniae strains and 11.46 percent of 218 E. coli strains during the study period. The generation of ESBL in the selected bacteria was shown to be on the rise.

Conclusion: In order to guide the use of antimicrobial drugs for the treatment of these pathogens in the hematopoietic stem cell transplant recipient population, screening for ESBL production among infectious K. pneumoniae and E. coli strains is critical.

Author (s) Details

Arij Mechergui
Laboratory Unit, The National Bone Marrow Transplant Centre, Tunis, Tunisia.

Wafa Achour
Laboratory Unit, The National Bone Marrow Transplant Centre, Tunis, Tunisia.

Assia Ben Hassen
Laboratory Unit, The National Bone Marrow Transplant Centre, Tunis, Tunisia.

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