Management of Post-Operative Pain and Quality of Life of Total Knee Arthroplasty Patients: A Prospective Study

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Management of Post-Operative Pain and Quality of Life of Total Knee Arthroplasty Patients: A Prospective Study

August 6, 2022 Pharmaceutical Pharmaceutical 0

The purpose of this study is to assess the effects of pregabalin on post-operative pain management and patients with osteoarthritis’ (OA) quality of life (QOL) after total knee arthroplasty.

The orthopaedics department conducted this prospective observational research. There were two groups each with 96 patients. 50 patients in Group A are treated with nonsteroidal anti-inflammatory medicines (NSAIDs), while 46 patients in Group B are treated with pregabalin. Over the course of six months, the research participants were given the knee injury and OA outcome score (KOOS) and visual analogue scale (VAS) questionnaires once every 60 days. The effectiveness of the therapy was assessed by comparing the follow-up score to the baseline score. In many cases, nonsteroidal anti-inflammatory medications (NSAIDs) are regarded as the best first therapy for OA.

The results of the study showed that the Group Bin VAS pain score at the conclusion of the study was 2.560.34 and the KOOS pain score was 92.733.45 (p0.01). When compared to Group A, the QOL score considerably increased to 81.565.29 (p0.01). According to the study, participants in the pregabalin + NSAIDs group improved their pain, symptoms, and quality of life faster than those in the NSAIDs alone group.

Author(s) Details:

T. Tamilselvan,
Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Keral-680588, India.

S. Rajasree,
Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Keral-680588, India.

S. Vineetha,
Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Keral-680588, India.

Arya Alocious,
Department of Pharmacy Practice, Nehru College of Pharmacy, Pampady, Keral-680588, India.

Please see the link here: https://stm.bookpi.org/CAPR-V5/article/view/7773  

Keywords: Osteoarthritis, total knee arthroplasty, pregabalin, nonsteroidal anti-inflammatory drugs, visual analog scale

 

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