Mechanisms of Prooxidants in Neuroinflammatory Processes and Clinical Manifestations

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Mechanisms of Prooxidants in Neuroinflammatory Processes and Clinical Manifestations

February 6, 2020 Medicine and Medical Science 0

In clinic practice the reduction of cerebral blood flow in particular zones of the brain as brainstem can cause early cerebral damage then, ischemia and posterior reperfusion induce an inflammatory response leading to further cellular death. Indeed, inflammatory cells may release deleterious compounds or cytokines that exacerbate oxidative damage to metabolically compromised neurons, and similar mechanisms may operate in the pathophysiology of neurodegenerative diseases in which vascular factors, inflammation and oxidative stress are implicated. In the present work, the issue referent to mechanisms of pro-oxidants in inflammatory processes and its relation with common pathogenesis and clinical manifestations are analyzed in detailed and updated form.

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Juárez Olguín Hugo
Laboratory of Neurochemistry, Instituto Nacional de Pediatría (INP), Mexico.
Laboratory of Pharmacology, Instituto Nacional de Pediatría (INP), Mexico.
Department of Pharmacology, School of Medicine, Universidad Nacional Autónoma de México, Mexico.
E-mail: [email protected], [email protected]

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