Polyamines: The Other Legacy of Antonie Van Leeuwenhoek
The aim of this brief chapter is to highlight Leeuwenhoek’s significant contributions to science through the invention of the microscope, an instrument that enabled him to observe a wide range of biological materials, including microorganisms, plant tissues, animal tissues, and observations in bodily fluids such as blood and sperm. He discovered spermine and other polyamine crystals in human sperm for the first time. We now know that these wonderful molecules control numerous roles in organisms and lead to homeostasis, despite the fact that he didn’t realise it. Polyamines have been studied in humans in both healthy and diseased states. Its involvement in hyperglycemic conditions is discussed here in relation to pancreatic function.
Author (s) Details
José D. Méndez
Medical Research Unit in Metabolic Diseases, Cardiology Hospital, National Medical Center, Mexican Institute of Social Security (IMSS), Mexico City, Mexico.
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