Research on the Lower Urinary Tract Infections among Patients Diagnosed of Benign Prostate Hyperplasia in Federal Medical Centre, Bida, North Central, Nigeria

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Research on the Lower Urinary Tract Infections among Patients Diagnosed of Benign Prostate Hyperplasia in Federal Medical Centre, Bida, North Central, Nigeria

September 25, 2020 Medical Science 0

This current study was aimed to identify the aetiology of bacteria associated with Benign Prostate
Hyperplasia (BPH) and to determine the antimicrobial susceptibility pattern of the isolated organisms
in the community. Urine samples were collected from a total of 536 patients with indwelling urinary
catheter on hospital admissions that were clinically diagnosed of BPH. Subjects were between the
ages of 41 and 100 years. Data was coded, computed and analyzed using SPSS version 16.0 and p
values ≤0.05 was considered to be statistically significant. Our research showed that the incidence of
urinary tract infections in this study population was (62.5%), and statistically not significant (p- value =
0.296, mean age=5.13, mode=4.00 and S.D ±2.03).
Escherichia coli 247(67.7%) was the most
prevalent uropathogen followed by
Staphylococcus aureus 34(9.3%), Pseudomonas species
29(7.9%),
Klebsiella species 10(2.7%), Proteus species 10(2.7%), Candida albicans 4(1.1%) and
Staphylococcus albus 1(0.3%) being the least isolates. The highest uropathogen was susceptible to
Nitrofurantoin (61.9%) followed by Levofloxacin (44.1%) and least susceptible to Gentamycin (12.1%),
Nalidixic acid (12.1%), Augmentin (7.7%) and Ampicillin (0.4%). Our research showed high incidence
rate of 62.5% of UTIs among patients with indwelling urinary catheter and diagnosed of benign
prostate hyperplasia in our community. This is of serious concern to all stake holders in health
industry. We observed that the most susceptible antimicrobial agent in this locality is Nitrofurantoin
(61.9%) and Levofloxacin (44.1%).

Author (s) Details

O. A. Akobi
Department of Medical Microbiology, Federal Medical Centre, Bida, Niger-State, Nigeria.

E. C. Akobi
Department of Nursing, Federal Medical Centre, Bida, Niger State, Nigeria.

E. G. Emumwen
Department of Medical Microbiology, Federal Medical Centre, Bida, Niger-State, Nigeria.

E. O. Uzoigwe
Department of Medical Microbiology, Federal Medical Centre, Bida, Niger-State, Nigeria.

E. F. Emumwen
Health Centre Clinic, Federal Polytechnic Bida, Niger-State, Nigeria.

P. O. Uyigue
Department of Medical Laboratory Science, Achiever University Owo, Ondo-State, Nigeria.

S. A. Akinola
Oyo-State Hospital Management Board, Ibadan, Nigeria.

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