Studies on Dexmedetomidine as an Adjuvant to Levobupivacaine in Ultrasound Guided Supraclavicular Brachial Plexus Block

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Studies on Dexmedetomidine as an Adjuvant to Levobupivacaine in Ultrasound Guided Supraclavicular Brachial Plexus Block

July 5, 2021 Medicine and Medical Science 0

Background: To prolong the duration of peripheral nerve blocks, alpha-2 agonists are added to local anesthetic agents. The goal of this study was to see how combining dexmedetomidine and levobupivacine affected the duration of motor and sensory block as well as the duration of analgesia. While the onset time of both sensory and motor blocks was shortened in the drug group in our study, the duration of analgesia was significantly prolonged. Materials and Methods: A prospective, randomized, double-blind study enrolled sixty ASA grade I or II patients aged 18-60 years for elective upper limb surgeries. The patients were split into two groups: control group B and study group BD. 30 ml of 0.325 percent levobupivacaine was given to group B (n = 30), and 30 ml of 0.325 percent levobupivacaine + 1 g/kg dexmedetomidine was given to group BD (n = 30) for ultrasound guided supraclavicular brachial plexus block. The duration of motor and sensory block, as well as the time to the first rescue analgesia, were all recorded. The demographic profile and surgical characteristics of both groups were similar. The onset times for sensory and motor blocks were significantly shorter in the BD group (p 0.05), but the duration of sensory and motor blocks, as well as the duration of analgesia (DOA), were significantly longer. Heart rate, SBP, and DBP levels were significantly lower in group BD 15-20 minutes after block (p 0.05). Two patients in the BD group developed bradycardia. There were no other negative effects observed in either group. Conclusion: Adding dexmedetomidine as an adjuvant to levobupivacaine for supraclavicular brachial plexus block significantly reduces the onset time and increases the duration of sensory and motor blocks, as well as the duration of analgesia.

Author (S) Details

Dr. V. Waindeskar
Department of Anaesthesia and Critical Care, AIIMS, Bhopal, India and People’s College of Medical Sciences & Research Centre Bhopal – 462037, India.

Dr. K. Bhatia
SHKM GMC Nalhar Mewat Haryana, India.

Dr. S. Garg
Department of Anatomy, Faculty of Medicine and Health Sciences, SGT University, Budhera, Gurugram, India.

Dr. J. Kumar
Department of Anaesthesia and Critical Care, AIIMS, Bhopal, India and People’s College of Medical Sciences & Research Centre Bhopal – 462037, India.

Dr. S. Songir
Department of Anaesthesia and Critical Care, AIIMS, Bhopal, India and People’s College of Medical Sciences & Research Centre Bhopal – 462037, India.

Dr. V. Singla
Civil Hospital Nuh, Mewat Haryana, India.

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