Synthesis of 4-Chloro-Piperidine Derivatives via NbCl5 Mediated Aza-Prins Type Cyclization of Epoxides and Homoallylic Amines
4-Chloropyperidine derivatives were synthesised under mild reaction conditions in good yield by reaction of epoxides and homoallylic amines using the Niobium pentachloride reagent.
Dr. Rajasekhar Koorella
Ragas Pharmaceuticals Private Limited (OPC), IDA Cherlapally, Hyderabad, 500051, India.
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