Synthesis and Potential Anti-Anxiety Activity of Some Novel Quinazolin-4 (3H)-One/Thione Derivatives

The current research work aims to synthesise some new sequence of quinazoline-4-one/4-thione derivatives by changing structures that preserve the fundamental structural characteristics of biological activity and screening various experimental animal models for their anti-anxiety activity. A sequence of derivatives of 7-chloro-3-[substituted (amino/phenyl amino)]-2-phenyl quinazoline-4(3H)-one/thione and 1-(7-chloro-4-oxo/-2-phenylquinazoline-3-(4H-yl))-substituted urea were prepared and characterised from various spectra and…
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January 14, 2021 0