Recent Study on Copper-Promoted One-Pot Approach: Synthesis of Benzimidazoles

For the production of various 2-arylaminobenzimidazoles, a simple, one-pot method was produced. For the first time, a copper catalyst promoted domino C–N cross-coupling reaction for the generation of 2-arylaminobenzimidazoles is used in this process. The synthetic pathway involves a copper-based desulphurization/ nucleophilic substitution followed by domino intra and intermolecular C–N cross-coupling reactions, according to mechanistic…
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March 13, 2021 0