Recent Study on Synthesis of Novel Pyrimido Oxazine and Their Derivatives
The present study used chalcone and urea as starting materials to make novel oxazine (1). The resulting compound 6-(4-chlorophenyl)-4-phenyl-6H-1,3-Oxazin-2-amine(2) was further reacted with ethyl 2-cyano-3,3-bis (methylthio) acrylate in DMF under reflux conditions, yielding novel 2-(4-chlorophenyl)-8-(methylthio)-6-oxo-4-phenyl-4,6,9,9 a-tetrahydro (3). Spectral methods were used to classify the synthesised compounds. At position 8, the compound (3) has a replaceable…
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