Acetamide Derivatives of N-Methyl Hydroxyaniliniumsulfate: Design, Synthesis, Spectral Characterization and in silico Study to Report them as Therapeutic Agents
Various biological activities have been found to demonstrate the compounds bearing sulfamoyl and acetamoyl groups. A series of O- and N-substituted derivatives, beginning with planetol (1), were synthesised in the present research work. Aq was used to treat the first N-methyl-4-hydroxyanilinium sulphate (1; planetol or metol) with various aryl sulfonyl chlorides (2a-j). Solution of sodium…
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