Inhibition of 6-Methylsulfinylhexyl Isothiocyanate for Cell Cycle Progression in Quiescent JB6 Cells Stimulated with Fetal Bovine Serum, Accompanied by Suppression of Cyclin A2 Expression

Wasabi contains a chemical called 6-Methylsulfinyhexyl isothiocyanate (6-MSITC) (Wasabia japonica Matsumura). In quiescent JB6 cells, 6-MSITC inhibited cell cycle progression when activated with epidermal growth factor. The goal of this work is to look into the mechanism of 6-MSITC’s inhibitory effects on cell cycle progression induced by foetal bovine serum (FBS). In serum-starved JB6 cells…
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December 17, 2021 0