Tag: Acetaminophen

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Phytochemical Appraisal and Evaluation of Effects of Aqueous Extract of Hypoestes rosea on Haematological Parameters of Acetaminophen – Induced Toxicity in Albino Rats| Chapter 10 | New Visions in Biological Science Vol.10

 Hypoestes rosea leaves are used as traditional medicine in most of Nigeria’s Niger Delta regions and the western portion of Cameroon to treat a variety of diseases and sick states in children, such as fever, anaemia, and malaria. Despite its widespread use, research on its phytochemicals and effects on haematological parameters is limited. As a…
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March 10, 2022 0

NRCT Clinical Study in to Identify Acetaminophen-Induced Liver Injury Mechanism

Acetaminophen (APAP) (N-acetyl-p-aminophenol) is a chemical compound utilised in paracetamol treatments to reduce pain and lower fever. In June 2009, an FDA advisory group issued a warning concerning the potential of APAP overdose due to the drug’s side effects, which include drug-induced liver damage. In addition, the FDA has begun collecting data on APAP toxicity…
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September 11, 2021 0

Tomato (Lycopersicon esculentum) Extracts Elicit Anti-Hepatotoxic Effects on Acetaminophen-Induced Liver Injury in Albino Wistar Rat

Introduction: Drug overdose is the largest cause of liver injury in the world today, according to numerous reports. Natural antioxidant-rich diets have been shown to provide significant relief from drug-induced organ damage. The goal of this investigation was to see if tomato extract could protect rats from acetaminophen-induced acute hepatotoxicity. Methods: Phytochemical tests were carried…
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August 24, 2021 0

Approach to Early Detection and Management of Kidney Disease

The effectiveness of glomerular filtration is measured by serum urea (sU), which is generated in the liver, and serum creatinine (sCr), which is a breakdown product of muscle cells. Both sU and sCr have low predictive accuracy for renal injury, especially in the early stages of kidney disease, because they are evaluated when 60-70 percent…
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July 22, 2021 0

A Narrative Review on the Effect of Acetaminophen and Ibuprofen in Orthodontic Tooth Movement

Application of orthodontic force causes an inflammatory event resulting in bone resorption and subsequent orthodontic tooth movement (OTM) in the periodontium. The release of inflammatory mediators such as E2 prostaglandins and Interleukin-1β serve as potent bone resorption stimulators. Strong force application results in discomfort and the same non-steroidal anti-inflammatory medications (NSAIDs) are recommended for relief.…
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October 17, 2020 0