The Protective Role of Adiponectin against Cerebral Ischemic Injury—Evidence from in vivo and in vitro Studies
Adiponectin (APN) is an adipokine abundant in circulation. Its main physiological function is involved in insulin sensitivity and regulation of metabolism of glucose and lipids. Besides, it has pleiotropic effects including anti-inflammation, anti-atherosclerosis, anti-thrombosis, promotion of endothelial repair, and angiogenesis which are protective in endothelial injury, atherosclerosis, and cardiovascular diseases. Evidence from current in vivo…
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