The Role of Adjunctive Psychosocial Interventions in Augmenting Clozapine Response in Patients with Clozapine Resistant Schizophrenia: A Review and Illustrative Patient Histories

A large proportion of patients with treatment-resistant schizophrenia continue to have persistent symptoms and psychosocial impairment despite adequate treatment with clozapine. This group of patients with clozapine resistant schizophrenia (CRS) constitutes about 40%-70% of those with treatment-resistant schizophrenia. These patients represent the most severely ill among those with schizophrenia with higher levels of symptom severity…
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July 27, 2020 0