Determination of Gastrointestinal Toxicity of Selective COX-2 Inhibitors in Comparison with Conventional NSAIDs
Background: The most prevalent side effects of NSAIDs are adverse gastrointestinal events, which are thought to be caused by the suppression of gastric COX-1, which is responsible for the manufacture of prostaglandins that typically regulate acid secretion and protect the mucosa. According to previous research, selective COX-2 inhibitors are safer than non-selective cyclooxygenase inhibitors when…
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