Tag: alloxan

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Determination of the Anti-diabetic Activity of Sphenostylis stenocarpa Seed Milk Extract in Alloxan-induced Diabetes Rats

Diabetes mellitus is a chronic metabolic disorder characterised by improper glucose, protein, and lipid metabolism. It’s generally connected with glycosuria, or the discharge of too much sweet urine. The majority of anti-diabetes medicines are not only expensive, but they also come with a significant level of drug toxicity. The anti-diabetic effect of seed milk extract…
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January 8, 2022 0

The Combination of L-lysine and Alloxan Induces Acute Necrotizing Pancreatitis in Rats: A Recent Study

The goal of this research was to see how L-lysine affected the pancreas of diabetic rats. Adult male Sprague-Dawley rats were split into four groups (each with six rats) and studied for 20 days. Control Group I (saline solution, i.p.). Group II: L-lysine (10 mM)-treated rats. Group III: Rats given 120 mg/kg of alloxan (diabetic…
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July 20, 2021 0

Evaluation of Anti-diabetic Potentials of Methanol Extract of Ficus hispida Linn. Leaves against Alloxan Induced Diabetic Rats

Objective: The present study was designed to evaluate the acute and chronic effects of the methanol extract of Ficus hispida against alloxan (150 mg/kg) induced diabetic rats. Methods: In acute study, hypoglycemic potency of methanol  extract of Ficus hispida was assessed by oral glucose tolerance test (OGTT) and in chronic study of 21 days, extract…
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February 3, 2020 0

Combined Anti-diabetic Effects of Extracts of Artemisia annua var. Chiknensis (CBGE/CHNA/09/LTNGS/G) and Each of Three Other Plants (Momordica charantia Linn. Vernonia amygdalina Del. and Aegle marmelos Correa) Traditionally Used in Nigeria for the Treatment of Diabetes

The combined anti-diabetic effects of Extracts of Artemisia annua var. chiknensis with Laboratory code number (CBGE/CHINA/09/LTNGS/G), Momordica charantia Linn, Vernonia amygdalina Del. and Aegle marmelos Correa traditionally employed in Nigeria for the treatment of diabetes were studied. Fifty male albino rats which had been subjected to overnight fasting were rendered diabetic through single intraperitoneal alloxan…
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September 26, 2019 0