Tag: antimalarial activity

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Antimalarial Activity of the Extracts of Vernonia Amygdalina Commonly Used in Traditional Medicine in Nigeria: An in vitro Study

In the tropics and subtropics, malaria is a serious infectious illness. Antimalarial drug resistance in P. falciparum has required the quest for new antimalarial agents. Vernonia amygdalina, a plant used by traditional healers to cure malaria and other ailments, was tested in vitro against 14 fresh isolates of Plasmodium falciparum from Damboa, Borno State, Nigeria.…
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August 21, 2021 0

Detils of the Preliminary Studies on Piliostigma thonningii Schum Leaf Extract: Phytochemical Screening and in vitro Antimalarial Activity

Medicinally, different parts of Piliostigma thonningii Scum (Caesalpinioideae) have been used. In the treatment of dysentery, fever, respiratory problems, snake bites, hookworm and skin infections in Eastern Nigeria, roots and twigs have been used locally. Leaf extracts have been used in Northern Nigeria for various ethnomedical purposes, including the treatment of malaria. The inhibitory effects…
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January 14, 2021 0

Preliminary Studies on Piliostigma thonningii Schum Leaf Extract: Phytochemical Screening and in vitro Antimalarial Activity

Different parts of Piliostigma thonningii Scum (Caesalpinioideae) have been used medicinally. The roots and twigs have been used locally in the treatment of dysentery, fever, respiratory ailments, snake bites, hookworm and skin infections in Eastern Nigeria. The leaf extracts have been used for various ethnomedicinal purposes including the treatment of malaria all over Eastern Nigeria.…
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September 24, 2020 0

Contribution in the Malaria Control of Substituted 5- chloro-3,4-dihydro-1H-pyrano[3,4-b]-1,10- phenanthrolinone Compounds: Antiplasmodial and Cytotoxic Activities

Background: Malaria is one of the most common parasitic disease in tropical and subtropical regions. Plasmodium falciparum, one of the causative agent of malaria is resistant to many type of antimalarial drugs. This study present in vitro assessment of the antiplasmodial activity of substituted phénanthrolinone compounds. Methods: A series of 7 substituents were used to…
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August 26, 2019 0

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