Measuring the Alkylation Kinetics and Drug Likeness of Four Novel Antineoplastic Compounds

Aims: To synthesize small molecule alkylating compounds and analyze the kinetics of the alkylation in aqueous solution. Determine molecular properties and the drug likeness of these four compounds as  potential  antineoplastic  agents  and  apply  statistical  analysis  to  identify  interrelationships  of properties. Study  Design: Four  compounds  were  synthesized,  characterized,  and  studied  for  alkylation capability.  The  alkylation …
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July 16, 2019 0