Tag: Antitumor activity

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Synthesis, Characterization and Biological Activities of Schiff Bases and Their Transition Metal Complexes

Schiff bases are versatile ligands that are generated by combining primary amines with carbonyl groups. Because of their broad range of biological activities, these compounds are extremely significant in the medical and pharmaceutical fields. The majority of them have biological properties such as antibacterial, antifungal, and antitumor properties. Transition metal complexes with biological activity derived…
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March 13, 2021 0

Determination of Antitumor Activity of Molecular Iodine Complexes with Lithium Halogenides and Bioorganic Ligands when Applied in Combination with Doxorubicin

The anti-tumor efficacy of iodine-containing anti-infective drugs with bio-organic ligands and potassium and lithium halides (LiCl(I)-I2-a-dextrin-peptide) has been investigated experimentally. The combined action of the LiCl(I)-I2-a-dextrin-peptide complex drug and doxorubicin on the growth of Ehrlich ascites carcinoma (EAC) has been shown to significantly enhance doxorubicin’s antitumor function. Using the quantum-chemical approach at the level of…
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October 17, 2020 0