Author(s) Details Andriy Yurachkivsky Department of Operations Research, Faculty of Computer Science and Cybernetics, Taras Shevchenko National University, Kyiv, Ukraine Read full Book: http://bp.bookpi.org/index.php/bpi/catalog/book/137
Metformin is the widely prescribed first line oral antidiabetic drug used in diabetes mellatus, type 2. The global sales turnover of metformin runs into millions of dollars. The Increased risk of metformin (Met) users for developing Alzheimer disease (AD) is reported first in a study conducted in 2011. Since then, the subject has attracted the…
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Background: Alcohol consumption accelerates the progression and worsens the outcomes of hepatitis C viral (HCV) infection in heavy and moderate drinkers. Non-structural NS5A protein is a known inducer of oxidative stress and carcinogenesis. Although alcohol consumption exacerbates the course of HCV-infection, the combined effects of NS5A protein and alcohol have not been studied and experimental…
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One female specimen of Basking shark Cetorhinus maximus (TL – total length = 245 cm, W – weight = 75 kg) was incidentally captured by a bottom trawler at a depth of about 25 m on 20 March 2014 from the off Yesilovacık coast (Mersin Bay, Turkey). Morphometric measurements presented in this paper. The present…
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Aims: Study leaf protein digestibility and effect of some antinutritional factors of Gnetum africanum and Gnetum buchholzianum on young male rats Wistar albinos. Study Design: Nutritional enhancement of use of Gnetum spp leafy vegetables. Place and Duration of Study: Limbe botanical Garden of Cameroon, between November 2013 and February 2014. Methodology: Proteins and antinutritional factors…
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Aims: To carry out the qualitative and quantitative phytochemical screening and assess the antimicrobial activity of banyan (Ficus benghalensis), castor (Ricinus communis) and clerodendron (Clerodendron inerme) leaf extracts. Place and Duration of Study: Department of Textile and Apparel Designing, College of Community Science, University of Agricultural Sciences, Dharwad, Karnataka, between July 2014 and June 2017.…
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The presence of fat, beyond physiological limits, in organs, other than the adipose tissue, like the liver, the skeletal muscle, the heart and the pancreas etc. is called ectopic fat. It causes specific organ dysfunction in the tissues concerned. The importance of the ectopic fat is that it is connected to peripheral tissue insulin resistance,…
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Simmondsia chinensis (jojoba) is a semi-hard wood perennial shrub grown on arid and semi-arid regions of the world. The stem cutting method is simple and efficient method for semi-hard wood plants to propagate vegetatively. The aim of this study was to investigate the best method of in vivo propagation through stem cutting of Simmondsia chinensis.…
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Fibrates are a class of medication that mainly lowers the blood triglyceride levels. They reduce the LDL and increase the levels of HDL C, in the blood. Clofibrate, the first member to be discovered in 1962, and introduced in USA in 1967, is withdrawn in 2002, due to unexplained hepatomegaly, hepato-toxicity and possible risk of hepatic cancer. Other fibrates are introduced…
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Aim: To analyze the most complex multi-subunit (MSU) DNA dependent RNA polymerases (RNAPs) of eukaryotic organisms and find out conserved motifs, metal-binding sites and catalytic regions and propose a plausible mechanism of action for these complex eukaryotic MSU RNAPs, using yeast (Saccharomyces cerevisiae) RNAP II, as a model enzyme. Study Design: Bioinformatics, Biochemical, Site-directed mutagenesis…
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