Tag: cytokines.

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Study on Alpha-2-macroglobulin: The New Weapon for Neuropathic Pains

From a biological standpoint, alpha-2-macroglobulin’s potential to generally suppress proteases in chronic and neuropathic pains, as well as inflammatory joint disorders, showed promise. Nerve damage and inflammation cause the release of cytokines. As a result of the inflammation, axonal damage and neuropathic symptoms may occur. Intradiscal autologous A2M injection indicated clinical improvements in a degenerative…
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February 1, 2022 0

Neuroimmunochemistry: A Short Review

Neuroimmunochemistry is a difficult field to master. Understanding the role of immune cells and manipulating them to improve neurodegenerative disease outcomes will be epigenetic medicine’s defining feature. The use of an immunologic strategy to investigate in-depth neural immunological interactions in order to combat neurodegenerative diseases such as brain stroke, tumours, Alzheimer’s disease, and multiple sclerosis…
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September 15, 2021 0

The Inflammasomes: Revamping Periodontal Pathogenesis

The discovery of inflammasomes, which are thought to govern the host immuno-inflammatory responses, has baffled the medical community recently. They are thought to serve a variety of purposes throughout the process, many of which are still unknown. Certain sensor proteins have been found to be essential for the assembly of inflammasomes in response to microbial…
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September 15, 2021 0

Recent study on Laboratory Development Cellular Immune Features and Immune Interference of Prototype Eschericia Coli and Pseudomonas Aeruginosa Combined Bacterins in a Lapin Model

Bacterial vaccinations, often known as bacterins, have both preventative and therapeutic properties. Autogenous bacterins, on the other hand, are critical in specific clinical situations, such as severe urinary tract infections. The purpose of this study was to look at the development, cellular immunological characteristics, and immune interference of E.coli and P.aeruginosa in rabbits. On a…
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September 15, 2021 0

Targeted Immunotherapy in Urological Malignancies

The treatment of urological cancers has been transformed by targeted immunotherapy. The method attempts to mimic the immune system’s natural ability to eliminate cancer cells. This can be accomplished by the use of non-specific treatments like recombinant Bacillus Calmette-Guerin (BCG) or particular agents such immune checkpoint inhibitors (ICI) and anti-tumor vaccines. The use of BCG…
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June 29, 2021 0

In vitro Studies on Proliferation and Production of Cytokine and IgG by Human PBMCs Stimulated with Polysaccharide Extract from Plants Endemic to Gabon

Polysaccharides were collected from seven Gabonese plants to investigate their immunological capacity. Proliferation, cytokine, and immunoglobulin G (IgG) assays in peripheral blood mononuclear cells (PBMCs) (5 105 cells/mL) were performed after stimulation with different concentrations of polysaccharide fractions, compared to lipopolysaccharides (LPS) and concanavalin A (ConA) from healthy volunteers. The culture supernatants were used in…
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May 14, 2021 0

The Role of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in Recognition of Pseudomonas aeruginosa in Lung Epithelial Cells: Detailed Study

Cystic Fibrosis Transmembrane Regulator (CFTR) plays an important role in chloride and thiocyanate ion homeostasis in human epithelial surfaces. Deletion of phenylalanine at position 508 (Δ508) leads to cystic fibrosis and dysregulation of pro-inflammatory cytokines. Pseudomonas aeruginosa gains predominance, contributing over 80% of the lung bacteria in adults with CF and this strongly correlates with…
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April 6, 2020 0

Alterations of Bronchial Cytokines in Bronchial Carcinoid Tumor Perioperatively

As bronchial carcinoids are known to be notably rare, adequate histochemical investigations couldn’t have been carried out on these types of tumors hitherto. In this study, we investigated bronchial cytokines in a carcinoid tumor localized in the left main bronchus. Bronchial resection and reconstruction was performed without the lung resection. Bronchial lavage samples were obtained…
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September 25, 2019 0