The Role of Cytoskeletal Proteins in the Regulation of Mitochondrial Function

Understanding muscle bioenergetics requires identifying mitochondrial roles and regulatory mechanisms, which is a key challenge in physiology/pathophysiology. Microtubules, intermediate filaments, and microfilaments are three cytoskeletal structures that play a critical role in mitochondrial structure/architecture, intracellular organisation, and motility. Furthermore, various cytoskeleton-mitochondrial contacts can actively contribute to the regulation of mitochondrial respiratory activity and oxidative phosphorylation…
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June 12, 2021 0