Sequential Cytotoxicity: A Theory Examined Using 2, 6 diphenyl Piperidine-4-one scaffold

The concept of sequential cytotoxicity indicates the successive release of two or more cytotoxic compounds causing grater toxicity to the neoplasm than normal cell. This hypothesis is evaluated by designing a series of compounds of 2, 6 diphenyl piperidine-4-one. Recently for the development of novel cytotoxic and anticancer agents, different series of compounds have been…
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June 8, 2020 0