A Comprehensive Review on Immune Checkpoint Inhibitor-induced Colitis

Immune checkpoint inhibitors (ICIs) are monoclonal antibodies that target anti-cancer immune response down-regulators such as cytotoxic T-lymphocyte antigen-4, programmed cell death protein-1, and its receptor programmed death-ligand 1. Checkpoint inhibitors are known to cause IMC, which is one of the most common side effects. The immune system plays a crucial role in detecting and removing…
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May 22, 2021 0