Tag: cytotoxicity

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Synthesis, Characterization and Biocompatibility of Maltodextrin-coated Cadmium Sulfide Quantum Dots in Experimental Models

Semiconductor Quantum dots (QDs) have acquire quite a bit of celebrity due to their characteristics and extensive application in organic and biomedical research. However, these very same features present further troubles in comprehending, concluding, and controlling possible unfavorable health results after exposure. These past few age, QDs have rapidly enchant and novel tools for theragnostic…
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January 19, 2023 0

Cytotoxicity Measurements of CdSe and Ag Hybrid Nano Composites for In-vitro Bioimaging Applications

The antimicrobial properties of silver metal have long been known. The interaction of these metal nanoparticles with human cells suggests that they are harmless. We synthesised a hybrid nanocomposites of Ag with Cadmium Selenide (CdSe) Quantum Dots (QDs) for cytotoxicity testing in this study. These hybrid nanostructures can be exploited in medical detection and therapy…
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May 28, 2022 0

Calcium Phosphate based Perforation Repair Materials using Human Gingival Fibroblasts: An in vitro Cytotoxicity Evaluation

New calcium phosphate cements (CPCs) have been discovered with promising physical properties for dental applications such as perforation repairs. However, there is a scarcity of data on the biological properties of these new materials, especially in long-term settings. We investigated the biological features of three distinct varieties of CPCs in a four-week in vitro cytotoxicity…
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May 25, 2022 0

The Role of In-vitro Cytotoxicity Assays to Confirm Non-toxicity Subsequent to the Detoxification Procedure of Mercuric Sulphide and Arsenic Trisulphide, Two Integral Metal Components Used in the Formulation of a Novel Herbo-mineral Antiviral Drug Targeted for COVID-19, ZingiVir-H

Herbo-mineral drugs are unique Ayurvedic metallic preparations that have been used in the treatment of various disorders by traditional medicinal practitioners for centuries in the Indian subcontinent. They have a number of advantages that have led to their widespread use in the treatment of various disorders by traditional medicinal practitioners. These benefits include improved stability,…
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April 26, 2022 0

A Comprehensive Review on the Pleotropic Role of Nitric Oxide, a Well-Known Cytotoxin

Nitric oxide (NO), a free radical, has a dual role in human physiology and disease. NO is thought to protect cells at low concentrations; but, at greater concentrations, it becomes cytotoxic and contributes to tumour angiogenesis and cancer growth. Although previous research on the function of NO in cancer were tissue-specific, this review focuses on…
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December 11, 2021 0

Could Methanol Leaf Extracts of Erythrina variegate L. be a Potential Source of Anticancer Molecule against Breast Cancer Cell Lines? – A Preliminary in vitro Investigation

Traditional/folklore medicine in India is reported to use Erythrina variegata L. (E. variegata) species in the treatment of cancer. As a result, the anticancer potential of this plant’s leaves might be investigated. The goals of this study were to: I assess the anticancer potential of crude extracts of E. variegata leaves using two solvents with…
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September 15, 2021 0

Synthesis, Antibacterial and Cytotoxicity Assessment of Modified Uridine Molecules

Nucleoside derivatives continue to play an important role in the treatment of various diseases; therefore, in light of the importance of nucleoside analogues, we synthesized a series of nucleoside molecules, namely, uridine derivatives. The direct acylation of uridine molecules with N-acetylsulfanilyl chloride produced the corresponding 5-O-N-acetylsulfanilyluridine with ribose sugar moiety. The 5 -O-N-acetylsulfanilyluridine derivative was…
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June 26, 2021 0

Assessment of the Cytotoxicity, Cell Cycle Arrest and Pro-apoptotic Effects of Two African Botanicals, Lantana ukambensis (Vatke) Verdc and Balanites aegyptiaca (L.) Delile on Human Colorectal Cancer Cells

In African traditional medicine, the plants Lantana ukambensis (Vatke) Verdc. (Verbenaceae) and Balanites aegyptiaca (L.) Delile (Zygophyllaceae) are used to treat wounds and inflammatory diseases. The aim of this study is to see how the extracts and fractions of these plants affect HCT-116 and HT-29 cells in terms of cytotoxicity, cell cycle arrest, and pro-apoptotic…
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March 4, 2021 0