Tag: Dasatinib

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Dasatinib and Quercetin: Short-term Simultaneous Administration Yields Senolytic Effect in Humans

Background: The higher the number of cell divisions, the more senescent cells. In human and animal beings, senescent cells are one of the most poisonous cells. When their number reaches a certain level, it causes a lot of ageing indicators to appear. During the division phase, the cell’s generation reaches ultimate morphogenetic state, according to…
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February 1, 2022 0

Determining the Enhancement of Oral Bioavailability VIA Solid Lipid Nanoparticles of Anticancer Drug Dasatinib – An In-vitro Cytotoxicity and Pharmacokinetic Study

Dasatinib (DST) is a Biopharmaceutics Classification System Class II medication with a high permeability and very low solubility. DST’s low water solubility and poor dissolution result in low bioavailability. As a result, restricted aqueous solubility represents a bottleneck for DST’s therapeutic success. Due to a large first-pass effect, animal research suggests that DST has an…
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September 20, 2021 0