Divalent and Trivalent Manganese Mixture Inhalation as a Parkinson Disease Model

The current study investigates the effects of divalent and trivalent Manganese (Mn2+/Mn3+) mixture inhalation on mice to create a novel animal model of Parkinson disease (PD), correlate those alterations with motor disturbances, and determine whether L-DOPA treatment improves the behavior to ensure that the alterations are of dopaminergic origin. For five months, CD-1 male mice…
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July 8, 2021 0