Molecular Docking and Pharmacokinetic Prediction Studies of Novel Coumarin Derivatives as Arylamine N- acetyltransferase 2 Inhibitors

Many medicines and carcinogens are detoxified by arylamine N-acetyltransferases, which are xenobiotic-metabolizing enzymes. It can bioactivate several recognised carcinogens by catalysing the N- or O-acetylation of different arylamine and heterocyclic amine substrates. The presence of NATs in the body has significant implications for an individual’s vulnerability to drug-induced toxicity and malignancy. The goal of this…
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September 20, 2021 0