Waldenstrom Macroglobulinemia / Plasma Cell Leukemia: A Diagnostic Dilemma
Waldenstrom macroglobulinemia (WM) is a subset of lymphoplasmacytic lymphoma and is categorized under mature B-cell lymphoid neoplasm. This lymphoproliferative disorder is characterized by infiltration of the bone marrow by a clonal lymphoplasmacytic infiltrate (≥10%) and an IgM monoclonal gammopathy. WM infiltrate comprises B–lineage cells with predominance of small lymphocytes, admixed with lymphoplasmacytoid cells, plasma cells…
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