CD4+ICOS+Foxp3+regulatory T cells: A Novel Sub-population Associated with Pathogenesis of Malaria
The protective immune response and disease outcome are known to be counterbalanced by regulatory T cells. The role of naturally occurring regulatory cells CD4+CD25+Foxp3+ in malaria infection remains debatable. ICOS molecule has been demonstrated to play a role in the growth and function of regulatory T cells and helps T regulatory cells to produce more…
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