Determination of Antitumor Activity of Molecular Iodine Complexes with Lithium Halogenides and Bioorganic Ligands when Applied in Combination with Doxorubicin

The anti-tumor efficacy of iodine-containing anti-infective drugs with bio-organic ligands and potassium and lithium halides (LiCl(I)-I2-a-dextrin-peptide) has been investigated experimentally. The combined action of the LiCl(I)-I2-a-dextrin-peptide complex drug and doxorubicin on the growth of Ehrlich ascites carcinoma (EAC) has been shown to significantly enhance doxorubicin’s antitumor function. Using the quantum-chemical approach at the level of…
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October 17, 2020 0