Tag: radiotherapy

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Radiation- Induced Trismus: A Concise Review of Pathogenesis, Prevention and Management

One of the most challenging side effects of anti-cancer therapy for patients with head and neck tumours is trismus (HNC). High-dose radiotherapy (RT), also known as radiation-induced trismus, has a high risk of inducing trismus in the temporomandibular joint, pterygoid, and temporalis or masseter muscles (RIT). Fibrosis in skeletal muscles, synovial fluid, extracellular matrix, and…
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August 8, 2022 0

Persistent Inflammation as a Cause of Severe Late Complications in Chemoradiotherapy-treated Head and Neck Cancer Patients

In head and neck squamous cell carcinomas, radiation, in particular concurrent chemoradiotherapy (C-CRT), considerably increases disease control and survival rates (HNSCCs). These improvements are, however, typically followed with a rise in the frequency of severe consequences that significantly reduce the patient’s functioning and quality of life and are primarily brought on by the underlying chronic…
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June 30, 2022 0

Temozolomide and Radiotherapy versus Radiotherapy Alone in High Grade Gliomas: A Very Long Term Comparative Study and Literature Review Up-to-date | Chapter 6 | Innovations in Science and Technology Vol. 6

 The goal of this study is to compare the outcomes of 31 patients who received RT and adjuvant TMZ (group A) from January 1997 to June 1999 versus 33 patients who received RT and concomitant TMZ (group B) from July 1999 to November 2001, as well as to compare the subjects who received both RT…
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March 12, 2022 0

Saliva as Biomarker of Heat Shock Protein 70 in Radiotherapy: A Clinical Approach

The human heat shock protein is made up of eight homologous chaperones: six in the reticulum and mitochondria, and two in the cytosol and nucleus. These proteins express differently in different tissues, hinting that they serve different biological activities. The levels of salivary Heat shock protein 70 in healthy people are compared to those in…
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October 21, 2021 0

A Retrospective Clinicopathological Study of Cervical Cancer

Cervical cancer remains the most common gynaecological cancer among women in developing countries. The purpose of this study was to look at the clinical presentation and histological pattern of cervix carcinoma over the course of three years. The research was done backwards. The patients were mostly in their 40s and 50s. The patients were mostly…
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September 18, 2021 0

Training and Evaluation of a Knowledge-Based Model for Automated Treatment Planning of Multiple Brain Metastases: An Advanced Study

Aim: Due to its capacity to give steep dose gradients around targets as well as modest doses to essential structures, volumetric modulated arc therapy (VMAT) has been used to plan and treat numerous cranial lesion metastases utilising a single isocenter. When compared to employing a single isocenter for each lesion, VMAT treatment takes significantly less…
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September 12, 2021 0

Fiducial Marker-Guided Radiotherapy Practices in Prostate Cancer Treatment

The fiducial marker application technique in prostate radiotherapy is an effective ancillary radiotherapy method for reducing acute and chronic radiotherapy side effects, safely administering higher doses, and contributing to local and overall survival without causing discomfort to the patient. It is non-invasive and risk-free. Patients are able to tolerate it well. It’s a crucial procedure…
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August 23, 2021 0

Radiotherapy in Elderly Patients with Low-Risk Breast Cancer

Few studies on the treatment of older women with low-risk breast cancer have been conducted. Despite the fact that their clinical behaviour is identical to that of younger patients, they are frequently undertreated, which increases the likelihood of local relapses and shortens their survival. The rate of local recurrences after breast conserving surgery without adjuvant…
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June 14, 2021 0

A Case Report on Primary Lymphoma of Liver Showing Non-Hodgkin’s B Cell Lymphoma

Lymphoma, also known as primary lymphoma of the liver or primary hepatic lymphoma, is a common liver cancer (PHL). It’s a rare form of non-lymphoma Hodgkin’s that causes hepatomegaly and cholestatic jaundice symptoms. This hepatic lymphoma has a positive prognosis if it is treated properly. We present a case of a 40-year-old man with an…
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May 3, 2021 0

Primary Leiomyosarcoma of the Prostate Gland: A Review and Update

PLSOP (primary leiomyosarcoma of the prostate) is a rare cancer, with just about 200 cases identified to date. PLSOPs are characterised by lower urinary tract symptoms, haematuria, and perineal pain; they may or may not be linked to a history of prior radiotherapy and/or hormone treatment for adenocarcinoma of the prostate; they may affect both…
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March 15, 2021 0